Benefits of lung-protective ventilation: looking beyond the ICU

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Benefits of lung-protective ventilation: looking beyond the ICU

Methods Objective: The aim of the study was to determine whether lung-protective ventilation improves outcomes in anesthetized patients undergoing major abdominal surgery. Design: The Intraoperative Protective Ventilation (IMPROVE) trial is a multicenter, open-label double-blind, parallel-group randomized control trial in seven French university hospitals. Setting: The IMPROVE study enrolled 40...

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provided the original work is properly cited. CC Hypoxemia and acute lung injury (ALI) are major concerns with one-lung ventilation (OLV) during thoracic surgery. Hypoxemia is usually the result of alveolar hypoventilation and an increasing shunt fraction, whereas ALI is caused by ventilatory stress (volutrauma, atelectrauma, and barotrauma), reexpansion pulmonary injury, and the lung surgery i...

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Are there benefits or harm from pressure targeting during lung-protective ventilation?

Mechanically, breath design is usually either flow/volume-targeted or pressure-targeted. Both approaches can effectively provide lung-protective ventilation, but they prioritize different ventilation parameters, so their responses to changing respiratory-system mechanics and patient effort are different. These different response behaviors have advantages and disadvantages that can be important ...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2014

ISSN: 1364-8535

DOI: 10.1186/s13054-014-0530-0